L-690,330 from Tocris Bioscience, a Bio-Techne Brand

614 McKinley Place N.E.

Minneapolis, Minnesota 55413

United States

Phone: 1 (800) 343-7475
1 (612) 379-2956
Fax: 1 (612) 656-4400

(1) LtpD is a novel Legionella pneumophila effector that binds phosphatidylinositol 3-phosphate and inositol monophosphatase IMPA1Infection and immunityNovember 1, 2013Harding CR, Mattheis C, Mousnier A, Oates CV, Hartland EL, Frankel G, Schroeder GN.

(2) Inhibition of inositol monophosphatase by lithium chloride induces selective macrophage apoptosis in atherosclerotic plaquesBritish journal of pharmacologyMarch 1, 2011De Meyer I, Martinet W, Van Hove CE, Schrijvers DM, Hoymans VY, Van Vaeck L, Fransen P, Bult H, De Meyer GR.

(3) A rational mechanism for combination treatment of Huntington's disease using lithium and rapamycinHuman molecular geneticsJanuary 15, 2008Sarkar S, Krishna G, Imarisio S, Saiki S, O'Kane CJ, Rubinsztein DC.

(4) Regulation of autophagy by the inositol trisphosphate receptorCell death and differentiationMay 1, 2007Criollo A, Maiuri MC, Tasdemir E, Vitale I, Fiebig AA, Andrews D, Molgó J, Díaz J, Lavandero S, Harper F, et al.

(5) Lithium induces autophagy by inhibiting inositol monophosphataseThe Journal of cell biologySeptember 26, 2005Sarkar S, Floto RA, Berger Z, Imarisio S, Cordenier A, Pasco M, Cook LJ, Rubinsztein DC.

(6) Wnt-5/pipetail functions in vertebrate axis formation as a negative regulator of Wnt/beta-catenin activityThe Journal of cell biologySeptember 1, 2003Westfall TA, Brimeyer R, Twedt J, Gladon J, Olberding A, Furutani-Seiki M, Slusarski DC.

L-690,330